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Cover | Challenge Journal of Perioperative Medicine

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Triple threat: Anesthetic approach to IVF twin gestation, pre-eclampsia and peripartum cardiomyopathy in caesarean section

Ranganath Laxman Channappagoudar, Chaitra Venkatesh Konappanavar, T. K. Darshini, Akanksha Priya

Challenge Journal of Perioperative Medicine (2025) 3(1) 21-25

Peripartum cardiomyopathy (PPCM) is a rare idiopathic condition frequently presenting with heart failure secondary to left ventricular systolic dysfunction towards the end of pregnancy or in the months following delivery. Can present as acute life-threatening ...
Neuraxial anesthesia in pregnant patients with neurological disorders ‒ Safety and practice strategies: A review

Mehmet Akif Yilmaz, Nuray Uzun

Challenge Journal of Perioperative Medicine (2025) 3(1) 14-20

Pregnant patients with neurological disorders face multifaceted challenges arising from both the physiological changes of pregnancy and the underlying neurological conditions. In this unique patient population, anesthesia management requires meticulous plannin...
The effects of lycopene in lung injury associated with cecum ligation and perforation-induced sepsis in rats: An investigative animal experiment study

Sumeyra Zeren, Ozgur Ozmen, Zekai Halici, Sare Sipal, Betul Gundogdu, Kamber Kasali, Nazim Dogan, Husnu Kursad

Challenge Journal of Perioperative Medicine (2025) 3(2) 32-39

Background: The primary aim of this study is to evaluate the effect of lycopene on serum interleukin-1ß (IL-1ß) and interleukin-6 (IL-6) levels in rats subjected to sepsis induced by the cecal ligation and perforation (CLP) method, as well as to assess the imp...
Effects on cardiopulmonary bypass duration and optic nerve sheath diameter changes

Tulay Cardakozu, Nur Nazire Yucal, Ali Ahmet Arikan, Sevim Cesur Okan, Oguz Omay

Challenge Journal of Perioperative Medicine (2025) 3(2) 40-47

Background: Cardiopulmonary bypass (CPB) causes disruption of the blood-brain barrier and cerebral autoregulation for many reasons. The resulting cerebral edema causes an increase in intracranial pressure. Ultrasonographic optic nevre sheath diameter (ONSD) me...
Mechanical properties assessment of recycled brick aggregate concrete using demolition waste from century-old masonry buildings in Nepal

Bipul Niroula, Mahesh Raj Bhatt

Challenge Journal of Concrete Research Letters (2026) 17(1) 41-56

This study explores the potential of recycling bricks from dismantled old buildings into brick aggregates and utilizing them as coarse aggregates in recycled brick aggregate concrete. Nepal, being susceptible to seismic events, generates large amounts of const...